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ICTR in the News: Allegheny Health Network Joins Johns Hopkins Clinical Research Network


The clinical research network is a program of the Johns Hopkins Institute for Clinical and Translational Research (ICTR), itself part of a national consortium aimed at transforming how clinical and translational research is conducted at academic health centers around the country. This article contains commentary from Daniel E. Ford, M.D., M.P.H., vice dean for clinical investigation at the Johns Hopkins University School of Medicine and director of the Johns Hopkins Institute for Clinical and Translational Research. Allegheny Health Network in Pennsylvania is the latest health system to join the Johns Hopkins Clinical Research Network. Developed by the Johns Hopkins Institute … Continue reading

ICTR in the News: Namandje Bumpus Named Science Commissioner


The following short article announces the appointment of ICTR researcher Namandje Bumpus, assistant professor of pharmacology and molecular sciences at the Johns Hopkins University School of Medicine. Namandje Bumpus, associate professor in the Division of Clinical Pharmacology, was nominated by the the mayor of the District of Columbia and confirmed by the city council as a science commissioner and the newest member of the Science Advisory Board in the District of Columbia. The board provides scientific oversight for the district’s Department of Forensic Science (DFS) and advises the DFS director, mayor and D.C. city council on matters relating to the department. Source: https://medicine-matters.blogs.hopkinsmedicine.org/2017/01/bumpus-named-science-commissioner/

ICTR in the News: Personalized Treatment for Those in Blood Pressure ‘Gray Zone’


The following article profiles work performed by ICTR researcher J. William McEvoy, M.B.B.Ch., M.H.S., assistant professor of medicine and member of the Ciccarone Center for the Prevention of Heart Disease at the Johns Hopkins University School of Medicine. Coronary artery calcium score gives risk assessment to prevent over- or undertreatment of blood pressure Using data from a national study, Johns Hopkins researchers determined that using heart CT scans can help personalize treatment in patients whose blood pressure falls in the gray zone of just above normal or mild high blood pressure. Previously, the appropriate blood pressure treatment for these patients used … Continue reading

ICTR in the News: U.S. patients often face costly ‘surprise’ medical bills from out-of-network specialists


Anesthesiologists, for example, charge almost six times what Medicare pays for the same service Article by: Stephanie Desmon The average anesthesiologist, emergency physician, pathologist, and radiologist charge more than four times what Medicare pays for similar services, often leaving privately insured consumers stuck with surprise medical bills that are much higher than they anticipated, new research published in the Journal of the American Medical Association suggests. The problem is that most patients do not actually choose these doctors with the highest markups, which mean they have no opportunity to anticipate how high their bills will be, say the researchers from the Johns … Continue reading

ICTR in the News: Potentially Reversible Changes in Gene Control ‘Prime’ Pancreatic Cancer Cells to Spread


The following article profiles work performed by ICTR researcher  Bert Vogelstein, M.D., professor of oncology at the Johns Hopkins University School of Medicine and the co-director of the Ludwig Center at the Johns Hopkins Kimmel Cancer Center. Epigenetic changes, not DNA mutations, drive some metastasis A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells. Those advantages, … Continue reading

ICTR in the News: Hospital Drones to Your House? (Video)


Featured in the below video is ICTR researcher Bruce Allen Leff, M.D., Director, The Center for Transformative Geriatric Research and a professor of medicine at the Johns Hopkins University School of Medicine. Source: http://www.politico.com/agenda/story/2017/01/video-hospital-drones-to-your-house-000273

Some Cells Need a ‘Haircut’ Before Duplicating


Study shows how and why hairlike structures on cells are lost Many of our cells are equipped with a hairlike “antenna” that relays information about the external environment to the cell, and scientists have already discovered that the appearance and disappearance of these so-called primary cilia are synchronized with the process of cellular duplication, called mitosis. Now, cell biologists at Johns Hopkins report the discovery of new information about how this “hair loss” and cell duplication are linked through the dramatic clipping of the tips of the cilia — what the scientists dub decapitation — that begins their disassembly. The … Continue reading