Johns Hopkins School of Medicine Clinical Research Restart Update   Jun 26, 2020 All the applications and review processes for clinical research restart updates are functioning at full capacity. Teams should continue to promptly submit the documentation they need to restart their protocols and start recruiting research participants. There are no significant delays for time to review.

Introducing the All of Us Researcher Workbench on Wednesday, July 1st at 11:00 am CT.  The All of Us Research Program aims to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care by providing researchers access to one of the largest biomedical datasets of its kind.  Guests will learn the All of Us Researcher Workbench and show how researchers use this platform to access and analyze All of Us data. This webinar is open to anyone who would like to attend – Registration is on the TIN Events webpage.

Jun 19, 2020 While clinical research has never totally stopped during the COVID-19 epidemic period, we are officially reopening our broader clinical research activity in the School of Medicine on Wednesday, June 24.

In a time-lapse video over eight hours, a high-powered microscope captures the moment when the CRISPR-Cas9 complex cuts two copies of a gene (red glow in blue circle and purple square) in a living cell. Scale Bar: 5 µm. Credit: Yang Liu, Johns Hopkins Medicine In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut. Results […]

Teamwork Reboot After COVID-19 Register This is a virtual workshop, links will be sent to those who register.   Overview Increasingly, high impact science is conducted in teams. Managing these teams may seem straight forward initially, but these teams can be fraught with challenges like communicating across disciplinary boundaries, aligning goals and incentives, sharing resources and credit. These challenges become more complex within the context of COVID-19. A deliberate approach to planning and applying the science of teams to these collective scientific endeavors is required. The overall goal of this two-part workshop is to provide to attendees with an introduction to fundamental […]

Patients around the world with severe COVID-19 illness are presenting with higher rates of vascular blood clots, so researchers at Johns Hopkins All Children’s Hospital have launched a national clinical trial to study the use of anti-clotting medications to treat children with the coronavirus and related diseases. Blood clotting is a natural reaction of the body to stop bleeding after injury, but in rare cases, the clots can block flow in blood vessels and cause a pulmonary embolism, stroke or other complications. Faculty physicians and colleagues in the Johns Hopkins All Children’s Institute for Clinical and Translational Research are studying low-dose anticoagulation — the use […]

June 12, 2020   Dear Colleagues: The university is adopting a phased plan for re-opening human participant research in line with its overall plan for re-opening. In preparation for having research staff and appropriate trainees access their research workspaces, each principal investigator (or group of investigators who share staff) needs to complete a clinical research reopening staff form. This form is separate from the processes to submit your human participant protocols for review for reopening.

Plan for the Return of Research with Human Participants at Johns Hopkins June 12, 2020 As efforts are underway to carefully consider the re-opening of activities across the University and Health System it is important that our research community prepares for a return of non-COVID-19 related research. While we do not yet know the exact time when restrictions for research with human participants will be lifted, we know that grant submissions, contract negotiations, and IRB activity have remained at a high level. Many research teams have maintained remote contact with research participants and we are all waiting to restart our […]

Courtesy of FDA.gov   CURE ID is an internet-based repository that lets the clinical community report novel uses of existing drugs for difficult-to-treat infectious diseases through a website, a smartphone or other mobile device. The platform enables the crowdsourcing of medical information from health care providers to facilitate the development of new treatments for neglected diseases. CURE ID is a collaboration between the FDA and the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH). FDA and NIH are also collaborating with the World Health Organization and the Infectious Disease Society of America to assess […]

Insights to Inspire: Making a Commitment to Diversity & Inclusion Insights to Inspire is a series of blogs and/or webinars highlighting the innovative and unique strategies implemented by a CTSA Program institution to improve on a given Common Metric. Mary Catherine Beach, MD, MPH and Stacey J. Marks, MS, were interviewed to discuss our Predoctoral Clinical Research Training Program in the story below.   The purpose of the Careers in Clinical and Translational Research metric is to measure the success of CTSA Program hubs in training scientists who will stay engaged in the field specifically with regard to underrepresented persons (URP) and […]