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Attend the Institutional Review Board (IRB) Open House May 17


The Johns Hopkins Office of Human Subjects Research is holding its 4th Annual Meet and Greet Open House on Friday, May 17, 2019. This is an opportunity to meet the staff, attend various workshops and find out everything you’ve always wanted to know about the IRB review process. Please register for one or more of the following courses: Help Desk FAQ’s 10:30 – 11:00 am & 1:00 -1:30 pm http://lms14.learnshare.com/l.aspx?CID=89&A=2&T=633010 Key Information and New Consent Form – Common Rule 10:30 -11:00 am & 2- 2:30 pm http://lms14.learnshare.com/l.aspx?CID=89&A=2&T=859954 Meet the Board Members 11–11:30 a.m. & 2:30–3 pm http://lms14.learnshare.com/l.aspx?CID=89&A=2&T=633006 New Exempt Categories … Continue reading

NCATS ASPIRE Design Challenge Submissions due May 31


The NCATS ASPIRE Design Challenges are designed to advance innovative and catalytic approaches towards solving the opioid crisis by developing “A Specialized Platform for Innovative Research Exploration” (ASPIRE) to aid in the discovery and development of novel and effective treatments, while at the same time making the process faster and more cost-effective. The NCATS ASPIRE Design Challenges are part of the of the NIH’s Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative will bolster research across NIH to (1) improve treatment for opioid misuse and addiction and (2) enhance pain … Continue reading

Elizabeth Jaffee Appointed to CStone Pharmaceuticals Scientific Advisory Board


Courtesy of SHANGHAI/PRNewswire/   CStone Pharmaceuticals (“CStone”; HKEX: 2616) is pleased to announce the appointment of three internationally renowned oncologists Paul A. Bunn, Jr., MD, Elizabeth M. Jaffee, MD, and Richard S. Finn, MD, as the company’s Scientific Advisory Board (SAB) members. With their deep scientific and medical expertise as well as extensive leadership and advisory experiences at top academic institutions, the addition of these three oncology leaders will greatly augment CStone’s Research and Development strategy in Immuno-Oncology and Precision Medicine and optimize the company’s drug portfolio as a whole. “It is our great privilege to have Drs. Bunn, Jaffee and Finn on our SAB. We … Continue reading

Psychedelic Drug MDMA May Reawaken ‘Critical Period’ in Brain to Help Treat PTSD


Johns Hopkins neuroscientists have found that the psychedelic drug MDMA reopens a kind of window, called a “critical period,” when the brain is sensitive to learning the reward value of social behaviors. The findings, reported April 3 in Nature, may explain why MDMA may be helpful in treating people with post-traumatic stress disorder (PTSD). Critical periods were first described in the 1930s in snow geese. About 24 hours after a gosling hatches, if mother goose is nowhere to be found, the hatchling will bond with an object, including non-living ones. Yet, if mother goose disappears 48 hours after her gosling … Continue reading

Third Thursdays with the ICTR April 18, What Epic Can Do for Your Research


We encourage all faculty, staff and students to attend. There will be a question and answer period at the close of each lecture. If you have suggestions for future topics, feel free to contact us. Attendees Will Learn: the basics for using Epic for research what services are available for researchers using Epic how Epic is currently being used for research To register, visit https://apr2019thirdthurs.eventbrite.com. For additional information, please contact Crystal Williams at cwill137@jhu.edu or visit: https://ictr.johnshopkins.edu/ThirdThursdays If you are unable to attend, you can view the lecture here. This lecture series showcases many of the resources, programs, educational training and other opportunities we … Continue reading

Doris Duke Early Clinician Investigator Award Seeking Applicants


Applications are due May 6, 2019 by 5:00 pm EST The Doris Duke Foundation has been committed to advancing clinical research for many years. Their review of the data has led them to the position that short term support for clinical researchers facing extra-professional demands could help them stay on a clinical investigation career track. With funding from the foundation and the School of Medicine, the Johns Hopkins Doris Duke Early Clinician Investigator Award aims to provide financial and mentoring resources for up 18 months to junior physician scientists who are working to have a productive career while also caring … Continue reading

Measuring Differences in Brain Chemicals in People with Mild Memory Problems


–Pilot study shows feasibility of measuring multiple brain metabolites simultaneously using noninvasive magnetic resonance spectroscopy to track development of Alzheimer’s disease Using strong and targeted but noninvasive magnets at specific sites in the brains of people with and without mild learning and memory problems, Johns Hopkins researchers report they were able to detect differences in the concentrations of brain chemicals that transmit messages between neurons. The strength of these magnetic fields allows the researchers to measure tiny amounts and compare multiple brain metabolite levels at the same time. These studies may ultimately help to reveal what initiates memory decline and … Continue reading

ICTR in the News: New Drug Combination Shows Promise for Common Pediatric Brain Tumors


This research features the work of ICTR Translational Research Community Co-Leader Barbara Slusher. Everolimus, Carboplatin Together Slow Low-Grade Glioma Tumor Growth, Reduce Tumor Size A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models. Researchers at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine combined carboplatin, a standard chemotherapy drug that works well against these brain tumors, and everolimus, which blocks an enzyme called mTOR that was shown in earlier research to fuel the growth of these tumors. The combination increased … Continue reading

Health Information Exchange Data Now Available to Johns Hopkins Researchers via the CRISP Research Initiative


Thursday, March 14th well over 100 faculty, staff members and students gathered to learn about the health information exchange database CRISP. The Chesapeake Regional Information System for our Patients (CRISP) is a non-profit health information exchange that serves Maryland, the District of Columbia, Virginia and West Virginia; and is designated as Maryland’s statewide health information exchange by the Maryland Health Care Commission. CRISP’s mission is to “enable and support the healthcare community of Maryland and our region to appropriately and securely share data in order to facilitate care, reduce costs and improve health outcomes.” Essentially, it electronically delivers the correct … Continue reading

Attend the Johns Hopkins inHealth Medicine Symposium May 30


Precision Medicine and the transformation of healthcare: advancing health using novel measurement, analysis, and communication. Thursday, May 30 from 8 am- 6:30 pm in Turner Concourse, come convene with national thought leaders in individualized health to examine the opportunity of improving patient care by discovering patient subgroups with secure cloud based data science. Become inspired by the precision medicine initiative at Johns Hopkins and learn about applications beyond the academic medical center setting. Explore an exhibit hall with over 20 core organizations that enable fundamental precision medicine functions including omics, biostatistics, and clinical research. For more information, follow the links … Continue reading

The American Statistician Special Issue: Moving to a World Beyond “p < 0.05”


“Moving to a World Beyond ‘p<0.05′”, in a special issue of The American Statistician (TAS), the lead editorial calls for abandoning the use of “statistically significant,” and offers much (not just one thing) to replace it. Written by Ron Wasserstein, Allen Schirm, and Nicole Lazar, the co-editors of the special issue, summarizes the content of the issue’s 43 articles. These articles discuss the use of p-values and statistical significance that Johns Hopkins researchers may find beneficial. To read the full article, click here.