Johns Hopkins Faculty Members Elected to National Academy of Medicine

Six faculty members of The Johns Hopkins University have been elected to the National Academy of Medicine (NAM). Announcement of new NAM members (85 total) was made today in conjunction with the academy’s annual meeting in Washington, D.C. The NAM is an independent organization of eminent professionals from diverse fields including health, medicine and the natural, social and behavioral sciences. It serves alongside the National Academy of Sciences and the National Academy of Engineering as adviser for the nation and the international community. Through its domestic and global initiatives, the NAM works to address critical issues in health, medicine and … Continue reading

Low Levels of Cellular Copper Linked to Fatter Fat Cells

Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar This article discusses the work of ICTR researcher Svetlana Lutsenko, Ph.D   In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar. The discovery, they say, adds to evidence that copper homeostasis could one day be a therapeutic target for metabolic disorders, including obesity. … Continue reading

Johns Hopkins Selected to Chart Genome Variations of 1 Million Americans

Focus will be on historically underrepresented samples in human genetic studies Credit: iStock The National Institutes of Health (NIH) has selected the Johns Hopkins University School of Medicine, Baylor College of Medicine and The University of Texas Health Science Center at Houston to lead one of three “genome centers” for its All of Us Research Program. The Johns Hopkins-Baylor team will receive inaugural funding of $7.9 million to begin collecting and analyzing clinical-grade genomic data from volunteers to understand how biological, environmental and lifestyle factors impact human health. “Creating this enormous data set from diverse populations will build a path to more … Continue reading

ICTR in the News: Electronic Health Records Need Organizing System

Abundance of Electronic Health Information Requires Organizing System to Make Best Use of Data The following article discusses the published work of ICTR Deputy Director of Informatics, Dr. Christopher Chute. Credit: iStock The rate at which electronic health data is accumulating is unprecedented, a Johns Hopkins health informatics expert notes in a review published Oct. 12 in the New England Journal of Medicine. To best make use of available information for personalized or precision medicine purposes, health organizations should consider using ontologies, a means of naming and organizing the information into categories for easier retrieval. Christopher G. Chute Credit: Johns … Continue reading

Free NIH Training in Neurotherapeutics Discovery and Development Course March 25-28

This training program in neurotherapeutics discovery and development is an intensive 3½ -day course that will provide trainees with the various knowledge elements required to discover and advance a neurotherapeutic agent to Investigational New Drug (IND) Application. Following the course, the training program will continue for a two-year period during which students will have individualized mentoring. The training, which is designed to be applicable to diverse diseases of the nervous system, will equip students with a broad understanding of the various component steps in the neurotherapeutics drug discovery and development process. The 2019 offering will be held at the Bethesda Marriott … Continue reading

Apply for the Research Accelerator and Mentorship Program (RAMP) Grant

The Johns Hopkins Clinical Research Network (JHCRN) is sponsoring a grant to promote inter-institutional research collaborations between Johns Hopkins Medicine and JHCRN affiliated institutions. This grant, Research Accelerator and Mentorship Program, will fund 1 to 3 projects, up to $50,000 over a 12-month period. Proposals including clinical and community-based research, practice-based research, and health services research are encouraged. Letters of intent are due by December 3, 2018 and complete applications are due by January 21, 2019. Eligible applicants include Johns Hopkins University faculty and JHCRN affiliate institution staff. Principal investigators are required to involve a minimum of one JHCRN affiliate institution co-investigator. JHCRN affiliated institutions include: … Continue reading

NCATS “Rare Diseases Are Not Rare!” Challenge Now Open

        NCATS is seeking innovative ways to communicate with others to educate people about rare diseases through social media or art. The goals of this challenge, which is being led by NCATS’ Office of Rare Diseases Research, are to raise awareness for all rare diseases in a collective manner, to bring attention to the many people with rare diseases and to highlight the need for research and the development of new treatments. Use any communication you choose; be as creative and original as possible! Examples of entries include a music video, poem, painting, poster, animation, song, comic, … Continue reading

NCATS Funding Opportunity: Pfizer’s Center for Therapeutic Innovation Program

          Proposal Portal Now Open; Pre-Proposals Due November 2   NCATS announces an opportunity for NIH intramural researchers to submit proposals to collaborate with Pfizer’s Centers for Therapeutic Innovation (CTI). Pfizer’s CTI program, which is managed by NCATS, pairs NIH intramural researchers with Pfizer resources to pursue scientific and medical advances through joint therapeutic development. Goals include identifying biologic compounds with activity in a pathway or target of interest to both an NIH intramural researcher and Pfizer and moving the compounds into the clinic to test them. Areas of interest to Pfizer include cancer, autoimmunity/inflammation, metabolic … Continue reading

Johns Hopkins Researcher Receives NIA/ORWH Center Grant to Study How Age and Sex Impact Immune Responses to Influenza Vaccines

Dr. Sabra Klein, an associate professor in the Johns Hopkins Bloomberg School of Public Health’s department of molecular microbiology and immunology, has received an $8 million grant from the National Institutes of Health to study how age and biological sex impact the immune responses to influenza vaccines. Despite having antivirals and vaccines, influenza remains a significant public health threat, causing approximately 100,000 hospitalizations, 30,000 deaths, and approximately $7 billion in lost productivity each year in the United States alone. Sex and age are emerging as two host variables that significantly impact the pathogenesis of influenza virus infection and responses to influenza … Continue reading

Save the Date: Trends in Clinical Research Seminar Nov 8

To Register: https://2018jhcrntrends.eventbrite.com For questions, please contact Melissa Gerstenhaber at mgerste1@jhmi.edu.

Register Now for NCATS Day 2018

        Participate in a robust dialogue about meaningful collaboration and help shape NCATS research priorities Don’t miss your opportunity to participate in NCATS Day 2018: Engaging Patients and Communities for Smarter Science on Sept. 28, 2018, from 8:30 a.m. to 5 p.m. on the NIH main campus in Bethesda, Maryland. This year’s event, which is focused on patient and community engagement, will provide a forum for participants to share and reflect upon patient and community needs as well as best practices for addressing those needs. Participants will learn strategies to broaden participation in research and to incorporate … Continue reading