ICTR in the News: 50 Years Ago, a Landmark Report Laid Bare the Racial Inequality Fueling Urban Unrest Across the Nation

Speakers at the conference detailed in this article will include ICTR researcher Lisa Cooper, Bloomberg Distinguished Professor, social epidemiologist, and health disparities researcher. Johns Hopkins co-hosts conference marking the 50th anniversary of the Kerner Report Article By: Katie Pearce Fifty years ago this week, a Washington Post headline put it plainly: “Chief Blame for Riots Placed on White Racism.” The newspaper had its hands on a fresh copy of the Kerner Report, the federal government’s analysis of riots in black neighborhoods in dozens of U.S. cities in 1967, including violent protests in Detroit and Newark, New Jersey, that left 70 … Continue reading

ICTR in the News: Accurate Telomere Length Test Influences Treatment Decisions for Certain Diseases

The following article profiles work performed by ICTR researcher Mary Armanios, M.D., professor of oncology at the Johns Hopkins Kimmel Cancer Center and clinical director of the Telomere Center at Johns Hopkins. Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure. In a report published in the Feb. 20 issue of Proceedings of the National Academy of Sciences, the researchers found that telomere length testing results also … Continue reading

‘Fentanyl Kills’ and Other Slogans: Hopkins Hackathon Focuses on Messaging Strategies That Could Save Lives

When it comes to the opioid crisis, some anti-drug slogans may be more effective than others, organizers from the Center for Communication Programs say Article By: Stephanie Desmon Andre was into drugs for 20 years, dealing them, using them, ending up in jail at times or homeless because of them. He tried again and again to quit. Five years ago, it finally stuck. “A pure miracle,” he called it. Now the 50-year-old from West Baltimore works with the advocacy group Bmore POWER as a peer educator and naloxone trainer. With so many messages about drug use coming from so many … Continue reading

Report Outlines Recommendations to Improve Student Mental Health and Well-Being

Two years ago, when Johns Hopkins medical student Davis Rogers read reports detailing the prevalence of depression among medical students and residents, he resolved to find a way to help promote mental health among his peers. When he was invited to join the Task Force on Student Mental Health and Well-Being—a cross-divisional group of Hopkins students, faculty, administrators, and staff—he saw it as fulfilling part of a personal mission. “This concept of mental health is not exclusive to patients in psychiatry or those who study it—it’s an issue that affects everyone, students included,” he says. After hearing concerns from members … Continue reading

ICTR in the News: Lead and Other Toxic Metals Found in E-Cigarette ‘Vapors’

The following article profiles work performed by ICTR researcher Ana María Rule, PhD, MHS, an assistant scientist in the Bloomberg School’s Department of Environmental Health and Engineering. Potentially dangerous levels of metals leak from some e-cigarette heating coils Significant amounts of toxic metals, including lead, leak from some e-cigarette heating coils and are present in the aerosols inhaled by users, according to a study from scientists at Johns Hopkins Bloomberg School of Public Health. In the study, published online in Environmental Health Perspectives on February 21, the scientists examined e-cigarette devices owned by a sample of 56 users. They found that significant numbers of … Continue reading

ICTR in the News: Cancer Risk Associated With Key Epigenetic Changes Occurring Through Normal Aging Process

The following article profiles work performed by ICTR researcher Stephen Baylin, M.D., the Virginia and Daniel K. Ludwig Professor of Cancer Research at the Kimmel Cancer Center. Some scientists have hypothesized that tumor-promoting changes in cells during cancer development—particularly an epigenetic change involving DNA methylation—arise from rogue cells escaping a natural cell deterioration process called senescence. Now, researchers at the Johns Hopkins Kimmel Cancer Center demonstrated that instead, tumor-associated epigenetic states evolve erratically during early stages of tumor development, eventually selecting for a subset of genes that undergo the most changes during normal aging and in early tumor development. The … Continue reading

ICTR in the News: Johns Hopkins Researchers Develop Single Blood Test That Screens for Eight Common Cancers

The following article profiles work performed in part by ICTR researchers Kenneth Kinzler, and Bert Vogelstein, professors of oncology. CancerSEEK is a noninvasive test that can detect cancers of the ovary, liver, stomach, pancreas, esophagus, colorectum, lung, or breast Article By: Amy Mone Researchers at the Johns Hopkins Kimmel Cancer Center have developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer. The test, called CancerSEEK, is a unique, noninvasive test that simultaneously evaluates levels of eight common cancer proteins and the presence of cancer gene mutations from DNA circulating … Continue reading

ICTR in the News: Five Novel Genetic Changes Linked to Pancreatic Cancer Risk

The following article profiles work performed by ICTR researcher Alison Klein, Ph.D., M.H.S. In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer. The new findings represent one more step toward fully capturing all of the genetic changes that lead to pancreatic cancer risk. This is important because a better understanding of how pancreatic cancer develops … Continue reading

Apply for the NCATS 2018 Omnibus Grant

The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) invites small business representatives to apply for the U.S. Department of Health and Human Services’ Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) 2018 Omnibus Grant Solicitation. The next application deadline is April 5, 2018, 5:00 p.m. local time for the following two opportunities: SBIR: PA-18-574 (R43/R44) STTR: PA-18-575 (R41/R42) Applicants to NCATS may address a range of its research priorities relevant to any stage of translational science, from target validation through pre-clinical and clinical evaluation, to intervention implementation and dissemination, including: … Continue reading

Number of Obese Years Not — Just Obesity — A Distinct Risk Factor for Heart Damage

In an analysis of clinical data collected on more than 9,000 people, Johns Hopkins researchers have shown that the number of years spent overweight or obese appear to “add up” to a distinct risk factor that makes those with a longer history of heaviness more likely to test positive for a chemical marker of so-called “silent” heart damage than those with a shorter history. The researchers say the findings suggest that maintaining a healthy weight across the lifespan is important for keeping the heart healthy and minimizing damage as people age. The authors caution that their study wasn’t designed to … Continue reading

ICTR in the News: Hospital Charges For Outpatient Cancer Care Highly Variable, Medicare Billing Records Show

Martin Makary, M.D., M.P.H., a cancer surgeon and professor of health policy at the Johns Hopkins University School of Medicine. Researchers call for “standard pricing” legislation to reduce financial burdens of vulnerable patients An analysis of recent Medicare billing records for more than 3,000 hospitals across the United States shows that charges for outpatient oncology services such as chemo infusion or radiation treatment vary widely and exceed what Medicare will pay by twofold to sixfold. A report of the findings, published in the American Journal of Managed Care on Feb. 17, emphasizes the need for fair and transparent pricing of … Continue reading