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Trial Innovation Network (TIN)

The TIN is designed to support innovation in multi-center clinical trials and studies.

The Trial Innovation Network (TIN) is composed of three key organizational partners – the CTSA Program Hubs, three Trial Innovation Centers (TICs) and one Recruitment Innovation Center.

In 2017, the Brain Injury Outcomes Division (BIOS) and the ICTR received a seven year, $25 million grant from the National Institutes of Health’s (NIH) National Center for Advancing Translational Sciences (NCATS) to form, along with the Tufts University School of Medicine, the Johns Hopkins-Tufts TIC.

The TIN’s vision is to innovatively address critical roadblocks in multi-center clinical trials and to accelerate the translation of novel interventions into life-saving therapies. The TIN is a collaborative national group that focuses on operational innovationoperational excellence and collaboration and leverages the expertise and resources of the CTSA Program.


The TIN features a single IRB system, master contracting agreements, quality-by-design approaches, and a focus on evidence-based strategies to recruitment and patient engagement.

The goal of the TIN is to execute trials better, faster, and more cost-efficiently, while also being a national laboratory to study, understand and innovate the process of conducting clinical trials.


The Johns Hopkins-Tufts TIC offers consultations to:

  • Provide investigators the opportunity to request feedback and resources for multi-center clinical and studies.
  • Help investigators develop proposals into protocols, enhance study operations, or improve recruitment and retention. Some consultations developed into clinical protocols may be implemented in the TIN and within the CTSA program

How to Work with Us

First, learn more about the proposal process and resources offered by the TIN. If you would like to submit a proposal, complete the brief intake form, which will go to the Johns Hopkins Hub Liaison point of contact.  The Hub will help you navigate the application process.

Please do not apply directly to the TIN without the assistance of the Hub Liaison Team.