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Clinical Trials Management System (CTMS)- formerly CRMS

The Clinical Trials Management System (CTMS), formerly the Clinical Research Management System (CRMS), is a web-based tool designed to organize and streamline clinical research management designed to improve communication among study team members.

OnCore Updates

Sprint 2 goes live Monday, April 29, 2024!

Effective October 5, 2023, there will be a new process for reporting CRMS issues. In conjunction with the OnCore* Sprint1 ‘Go-Live’, [email protected] will be deactivated and replaced with a new helpdesk process. To create a CRMS helpdesk ticket, visit the Service Portal – Johns Hopkins Medicine ( portal (and enter your JHEDID if prompted). Or, you can use any of the following options:

  1. Submit Ticket:  JH Portal ( à Helpdesk à Epic Help
  2. Phone:  410-614-EPIC (3742)
  3. HCGH:  410-740-7813; option 2
  4. SH:  301-896-HELP (4357); option 2
  5. SMH:  202-537-HELP (4357); option 2
  6. ACH:  727-767-4884; option 2

For questions regarding the launch or to enroll in a training, visit the Resource Hub. You can also subscribe to the OnCore News mailing list.

* OnCore is a Clinical Research Management System that will fully replace our current Clinical Research Management System (CRMS) by April 2024. Between October 5, 2023 (Sprint 1 Go Live) and April 29, 2024, OnCore will be used for new IRB submissions (submitted after October 5, 2023) from SKCCC and a small set of ongoing SKCCC studies, and new IRB submissions and a small set of ongoing studies for pre-selected Principal Investigators from the DOM. All other studies will continue to use CRMS until April 29, 2024 (Sprint 2 Go Live) when CRMS will be permanently retired and we will switch completely to OnCore for all clinical trials. OnCore will serve as a single, centralized, web-based enterprise resource to support clinical research studies conducted by JHM. OnCore has enhanced functionality including providing financial reporting visibility, increasing efficiency of billing compliance review & improve invoicing frequency for externally sponsored trials, harmonizing data entry and documentation, improving study compliance and facilitating collaboration with other research institutions on the same platform.

CRMS has the following main features:

  • Protocol information from eIRB2
  • Registry of study participants
  • Management of study accruals
  • Consent tracking
  • Secure location for study-related documents
  • Pre-configured and adhoc reports
  • Multiple interfaces with Epic, including sending data to Epic about the study and the study participants

CRMS must be used by studies which could result in a patient bill. It may also be used by retrospective studies to define the study cohort in order to facilitate data extraction from Epic and other information systems.

If you are already a CRMS user, you can access the software at

For more information about CRMS, visit (This website requires that you are on campus or are using VPN.)