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OnCore Clinical Trials Management System (CTMS)

The OnCore Clinical Trials Management System (CTMS), is a web-based tool designed to organize and streamline clinical research management designed to improve communication among study team members.

OnCore serves as the Clinical Trial Management System, facilitating clinical research operations at Johns Hopkins Medicine. This online platform enables thorough management of clinical research studies, offers robust reporting capabilities, facilitates enrollment tracking, and ensures accurate clinical research billing.

All studies with a prospective reimbursement analysis (PRA) will require the use of OnCore. For studies without a PRA, the use of OnCore is optional.

Please let us know if you have any questions or concerns by contacting [email protected]. For technical support needs, please submit a help desk ticket.

Visit the OnCore and eReg Support Page for access to training and production environments.

For questions regarding the launch or to enroll in a training, visit the Resource Hub. You can also subscribe to the OnCore News mailing list.


To create a CRMS helpdesk ticket, visit the Service Portal – Johns Hopkins Medicine (service-now.com) portal (and enter your JHEDID if prompted). Or, you can use any of the following options:

  1. Submit Ticket:  JH Portal (my.jh.edu) Helpdesk Epic Help
  2. Phone:  410-614-EPIC (3742)
  3. HCGH:  410-740-7813; option 2
  4. SH:  301-896-HELP (4357); option 2
  5. SMH:  202-537-HELP (4357); option 2
  6. ACH:  727-767-4884; option 2