Clinical Research Units
Effective May 2018, the CRUs will operate using a service center model and certain associated resources require a CRU Online application and approval.
The Clinical Research Units (CRUs) provide resources at 3 locations throughout the medical campuses–Johns Hopkins Hospital, the Charlotte R. Bloomberg Children’s Center and the 301 Building on the Johns Hopkins Bayview Medical campus. The CRUs are the safest, most efficient way to perform clinical and translational research and offer an indispensable resource that is widely used and required by our NIH funded investigators. Through protocol review, investigator mentoring, trained nursing staff, protocols performed on the CRUs are planned, vetted, monitored and performed under a similar safety standard to clinical care. The CRUs are staffed by experienced research nurses and the protocols are reviewed for scientific rigor, appropriateness of resources and for patient safety by the IRB and CRU review mechanisms. The CRUs are available for investigators needing outpatient, inpatient, adult, pediatric, or neurological services.
Click the links below to learn more about each service:
Applying to Use the CRUs
All investigators must submit an application to a Johns Hopkins Institutional Review Board (IRB) before beginning their ICTR Clinical Research Units (CRUs) application.
Submit Request & Join Our Listserv All CRU protocols are reviewed by a member of the Biostatistics Core prior to approval, and consultations with a Core biostatistician are strongly encouraged.
Cardiovascular Imaging Laboratory
The Cardiovascular Imaging Laboratory is located at the Bayview CRU and is supervised by Pamela Ouyang, MBBS, ICTR Deputy Director and Director of the Johns Hopkins Women’’s Cardiovascular Health Center.
Future Charges For Clinical Research Unit Services
Effective May 2018 The National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health (NIH), which supports the ICTR Clinical Research Units (CRUs) through its Clinical and Translational Science Award (CTSA) program.
Exercise Physiology and Body Composition
The Exercise Physiology and Body Composition Core’s laboratory provides DEXA measurements for body fat, muscle and bone composition, metabolic stress testing, and also supports exercise-training protocols.
Bayview Clinical Research Unit: The ICTR Bayview Clinical Research Unit (Bayview CRU) is located on the 4th Floor of 301 Mason Lord Drive on the Johns Hopkins Bayview Campus.
Nursing Research Resources
A broad scope of nursing services is offered in the CRUs, ranging from routine vital signs to intensive studies requiring intravenous infusions and specialized measures.
Neurological and Behavioral Sciences
Advances in the neurological and behavioral sciences continue to offer unprecedented opportunities to better understand and treat disorders of the central nervous system.
Neuroimaging resources available through the NBRU include structural and functional magnetic resonance imaging, spectroscopic and diffusion analysis, fiber track mapping, fMRI protocol development.
Pediatric Neuropsychological Testing
Neuropsychological testing, includes achievement tests, behavior checklists, measures of personality, developmental status, intelligence, executive function, language, visual spatial skills, and memory, are available to ICTR CRU investigators.
Pediatric Motion Analysis Laboratory
The Pediatric Motion Analysis Laboratory is available through the NBRU in the Kennedy Krieger Institute. The lab provides whole-body movement assessments that quantify discrete components of the mechanisms of movement and movement deficits.
Operant Performance Measures
State-of-the-art Operant Performance Measures are available to investigators through the NBRU at Kennedy Krieger Institute. Direct observation of behavior, conducted in areas that simulate naturalistic settings.
Research Participant Advocacy
Research Participant Advocacy (RPA) Program The RPA serves as a resource to volunteers. Contact us for an independent witness to the consent process, to serve on the volunteers behalf.
ICTR Research Nutrition was established to support CRU investigators in developing and implementing the best nutritional plans for their research protocols for both pediatrics and adults.
Research Coordinator Support Service
The ICTR Research Coordinator Support Service (RCSS) is a pool of research coordinators that are available for hire on a part-time basis by Johns Hopkins researchers.