Centralized Registry for COVID-19 Research Recruitment: Design, Development, Implementation, and Preliminary Results
Background
The COVID-19 pandemic has had substantial global morbidity and mortality. Clinical research related to prevention, diagnosis, and treatment COVID-19 is a top priority. Effective and efficient recruitment is challenging even without added constraints of a global pandemic. Recruitment registries offer a potential solution to slow or difficult recruitment.
Objectives
The purpose of this paper is to describe the design and implementation of a digital research recruitment registry to optimize awareness and participant enrollment for COVID-19 related research in Baltimore and to report preliminary results.
Methods
Planning began in March 2020, and the registry launched in July 2020. The primary recruitment mechanisms include electronic medical record data, post-cards distributed at testing sites, and digital advertising campaigns. Following consent in a REDCap survey, participants answer questions related to COVID-19 exposure, testing, and willingness to participate in research. Branching logic presents participants with studies they might be eligible for.
Results
As of March 24th, 2021, 9,010 participants have enrolled, and 64.2% are female, 80.6% are white, 9.4% are Black or African American, and 6% are Hispanic or Latino. Phone outreach has had the highest response rate (13.1%), followed by email (11.9%), text (11.4%), and patient portal message (9.4%). Eleven study teams have utilized the registry, and 4,596 matches have been made between study teams and interested volunteers.
Conclusion
Effective and efficient recruitment strategies are more important now than ever due to the time-limited nature of COVID-19 research. Pilot efforts have been successful in connecting interested participants with recruiting study teams.
Peeler, A., Miller, H., Ogungbe, O., Lewis Land, C., Martinez, L., Guerrero Vazquez, M., Carey, S., Murli, S., Singleton, M., Lacancieta, C., Gleason, K., Ford, D., Himmelfarb, C. (2021). Centralized Registry for COVID-19 Research Recruitment: Design, Development, Implementation, and Preliminary Results. Journal of Clinical and Translational Science, 1-25. doi:10.1017/cts.2021.819
