Tag Archive: Previous Consulting Services

Henrietta Lacks


Henrietta Lacks was an African-American woman who underwent treatment for an aggressive form of cervical cancer at Johns Hopkins Hospital in 1951.  In addition to providing her with medical care, Henrietta’s doctor at Hopkins removed some of her cancerous cells to use in research without getting her written consent, which was a routine practice in medicine at the time. Despite receiving a high standard of medical treatment, Mrs. Lacks ultimately succumbed to this cancer at the young age of 31.  However, her extraordinary cells—called “HeLa” from the first two letters of her first and last names—continued to reproduce in the … Continue reading

The Henrietta Lacks Memorial Lecture


The Johns Hopkins ICTR is privileged to be the establishing sponsor of the Henrietta Lacks Memorial Lecture Series. The goal of the series is to honor Henrietta Lacks and the positive global impact of HeLa cells. This series will also serve as an annual reminder of the gratitude, respect, and clear communication due to all research participants. Keeping biomedical research connected to the people it is intended to serve is an ongoing process rooted in the open exchange of ideas among all stakeholders. To facilitate this process, speakers for the Henrietta Lacks Memorial Lecture Series are selected for their ability to … Continue reading

School Visits and Youth Symposium


In the first half of 2012, over 200 students and teachers from regional middle and high schools were invited to the Johns Hopkins medical campus to further engage students outside of the classroom after reading The Immortal Life of Henrietta Lacks. Students were privileged to hear from Mrs.Lacks’ grandson, Ron Lacks, about the evolving relationship between Johns Hopkins and the Lacks family.  Many labs even opened their doors to invite students to see working stem cell labs, including viewing HeLa cells.  Another core portion of the visit to Johns Hopkins for students is a bioethics discussion. On Monday, March 24, … Continue reading

In the first half of 2012, over 200 students and teachers from regional middle and high schools were invited to the Johns Hopkins medical campus to further engage students outside of the classroom after reading The Immortal Life of Henrietta Lacks. Students were privileged to hear from Mrs.Lacks’ grandson, Ron Lacks, about the evolving relationship between Johns Hopkins and the Lacks family.  Many labs even opened their doors to invite students to see working stem cell labs, including viewing HeLa cells.  Another core portion of the visit to Johns Hopkins for students is a bioethics discussion.

On Monday, March 24, 2014, Johns Hopkins East Baltimore Community Affairs and Johns Hopkins Institute for Clinical and Translational Research hosted the 2014 Henrietta Lacks Baltimore City Youth Symposium. In an effort to supplement classroom learning, the symposium invited 350 Baltimore City high school students to Johns Hopkins in an effort to introduce real-life research initiatives, career paths, and discussion based around HeLa stem cells and biotechnology.  The symposium also offered an opportunity for students to further understand bioethics through history and today.  The day concluded with a panel-style Q&A featuring members of the Lacks family.

The video above was filmed on that day and captures key aspects of the program.

 

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Medicinal Chemistry Unit


The Medicinal Chemistry Unit synthesizes small molecule when it is not commercially available.  This unit also supports structure-activity relationship studies. For more information, contact David Meyers, PhD.   Click here to submit an ICTR Connection Request

Metabolomics Program


The Metabolomics Program: Provides consultation to basic, clinical, and translational research teams regarding the feasibility, design, and costs of projects using metabolomics technologies (including mass spec and NMR-based metabolomics); Customizes metabolic approaches based on specific research projects/questions: ranging from simple assays to high-throughput approaches such as global metabolic profiling and stable isotope-13C, 15N-labeled on a wide variety of sample types; Provides extensive data analysis and suggest options for subsequent steps towards clinical implementation.   Click here to submit an ICTR Connection Request

Imaging Translational Program


The Imaging Translational Technology Core (Imaging TTC) facilitates one-on-one consultation with imaging experts for study design, imaging protocol development and study implementation. The core facilitates integrated use of imaging resources in translational projects and clinical trials and offers research imaging management infrastructure through the Johns Hopkins Medical Image Research Archive Center for research data storage and distribution Imaging also offers CORIS, a one week observership program for anyone interested in radiology. Participants have an opportunity to shadow Katarzyna (Kasia) J. Macura, MD, PhD, FACR, Professor of Radiology, Urology and Oncology. For more information and to schedule a time, contact Atefeh Ameri at … Continue reading

Proteomic Biomarker Development Program


Proteomics Facility couples mass spectrometry to one and two dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are present in complex protein extracts or isolated in solution, gel bands or spots from cells, tissues or body fluids. Metabolite profiling for small molecules from clinical samples Provides biomarker development support Marker verification, validation, qualification for clinical implementation Provides technology and analysis to maximizes coverage of key proteomes required for discovery Quantitative protein analysis methods including mass spectrometry and development of new technologies Click here to submit an ICTR Connection Request

Drug Screening Library Unit


The Drug Screening Library Unit maintains, distributes, and screens drug library (FDA approved) compounds.  This unit is ideal for re-purposing licensed drugs by screening activity against new targets. For more information, contact Jun Liu, PhD.   Click here to submit an ICTR Connection Request

Drug Development Unit


The Drug Development Unit provides: Consultative support for early phase clinical drug development Protocol design and data analysis support Early phase clinical study support   Click here to submit an ICTR Connection Request

Drug Analysis Unit


The Drug Analysis Unit provides support for drug development activities to faculty and to solicit use by faculty of Core expertise and facilities. Activities include consultative expertise and laboratory support. The unit offers support in the areas of: Small molecule assay development Sample analysis for pre-clinical and clinical studies Pharmacokinetic data analysis support Consultative support for pre-clinical study design   Click here to submit an ICTR Connection Request

Biologics Translational Program


This lab offers: Biologic product development and testing Consultative support for biologic development Preclinical testing to clinical production for early phase clinical testing Good Manufacturing Practices (GMP) facility and expertise to produce and maintain (stability testing Cell lines Gene vectors Antibodies Peptides   Click here to submit an ICTR Connection Request