Tag Archive: Imaging

Drug Discovery Development Core

Posted by: Michelle Diaz on: June 11, 2019

A collaboration between Johns Hopkins University and the University of Maryland. Discovery & Early Development Medicinal Chemistry Unit Reference compound synthesis to synthesize commercially unavailable compounds of key biological and pharmacological interest to core users as reference and/or tool compounds. Contact: Takashi Tsukamoto, PhD., 443-629-7984, ttsukamoto@jhmi.edu David Meyers, PhD., 410-502-4804, dmeyers7@jhmi.edu Assay Development and Screening Unit Biochemical and assay development support will assist biochemical assays development for putative therapeutic targets along with Cell-based assay development support that will facilitate development of cell-based drug screening assays. The Drug Screening Library maintains, distributes, and screens drug library (FDA approved) compounds. This library […]

ICTR in the News: 3D Imaging and Computer Modeling Capture Breast Duct Development

Posted by: Crystal Williams on: June 18, 2018

The following article profiles work performed by ICTR researcher Andrew Ewald, Ph.D., professor of cell biology at the Johns Hopkins University School of Medicine and a researcher at the Johns Hopkins Kimmel Cancer Center. Working with hundreds of time-lapse videos of mouse tissue, a team of biologists joined up with civil engineers to create what is believed to be the first 3D computer model to show precisely how the tiny tubes that funnel milk through the breasts of mammals form. A report on the model was published April 9 in Developmental Cell. The model employed science and engineering principles commonly […]