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Study Shows How Breast Milk Protects Against Severe Intestinal Disease in Preemies


The immune-boosting properties of breast milk have long been known. Now a team of scientists led by Johns Hopkins pediatric surgeon-in-chief David Hackam, M.D., Ph.D., says experiments in mice reveal how breast milk works to ward off the development of necrotizing enterocolitis (NEC), a devastating intestinal disorder that affects 12 percent of premature babies and claims the lives of one in four of those who have it. If affirmed in human studies, the experiments could pave the way to new preventive approaches to stave off NEC in premature babies and spark the development of treatments for those who develop the […]

PTSD Common in Intensive Care Unit Survivors


–Nearly one-quarter of intensive care unit survivors have post-traumatic stress disorder; diaries could be successful prevention tool Fast Facts Research finds that one-quarter of patients who survive a critical illness and an ICU stay experience PTSD. Researchers are looking into using ICU diaries as a promising therapeutic tool to prevent PTSD in ICU survivors. Existing psychological problems, large amounts of sedation and reports of frightening ICU memories appear to contribute to the increased risk of PTSD in ICU survivors. Post-traumatic stress disorder is often thought of as a symptom of warfare, major catastrophes and assault. It’s rarely considered in patients […]

Tumor-Only Genetic Sequencing May Misguide Cancer Treatment in Nearly Half of All Patients


–Johns Hopkins scientists say the genetic code of tumors must be compared to patients’ noncancer genome to get a true picture A study by Johns Hopkins scientists strongly suggests that sequencing tumor genomes for clues to genetic changes might misdirect treatment in nearly half of all patients unless it is compared first to a genetic readout of their noncancerous tissue. The investigators at the Johns Hopkins Kimmel Cancer Center say their analysis of more than 800 cancer patients’ sequencing data, which was generated by Personal Genome Diagnostics Inc., a company co-founded by the researchers, shows that without such comparisons, attempts […]

Johns Hopkins-Sun Yet sen Researchers Discover Autism Gender Differences


The article below was featured in Eureka Alert and discusses research findings from a study supported by a grant from Johns Hopkins Medicine International SYSU-JHU Pilot Grant Program on Clinical and Translational Research.   SAN DIEGO – Girls are diagnosed with autism spectrum disorder (ASD) later than boys, possibly because females exhibit less severe symptoms, according to a study to be presented Tuesday, April 28 at the Pediatric Academic Societies (PAS) annual meeting in San Diego. To study gender differences in age at diagnosis and compare symptom severity between boys and girls, researchers at the Kennedy Krieger Institute in Baltimore, MD, […]

ICTR Deputy Director Receives Excellence in Teaching Award


The article below honors Toby Gordon, ScD, ICTR Deputy Director of Business Strategies. Johns Hopkins Carey Business School Associate Professor Toby Gordon has been recognized with an Excellence in Teaching Award from students in the 2013-2015 cohort of the MBA/Master of Public Health dual-degree program offered by the Carey School and the Johns Hopkins Bloomberg School of Public Health. Gordon, who earned her ScD in health policy and management from the Bloomberg School, has expertise in the areas of health care policy, management of hospitals and health systems, and technology commercialization. She has joint appointments at the Bloomberg School and the […]

Successful Pharmaceutical Study Start-Up: Key Steps for New Investigators


Click here to register: Nearly 70% of clinical trials experience start-up delays, 45% are completed late, and 20% of sites recruit zero patients (Source: Centerwatch 2014). New Investigators: Don’t become a statistic! The Johns Hopkins Clinical Research Network invites you to attend Successful Pharmaceutical Study Start-Up: Key Steps for New Investigators. The seminar will take place on Monday, November 9, 2015 from 3:00 – 5:00 p.m., in the Tilghman Auditorium. Experts from the Office of Research Administration, Clinical Research Support Services, JHM IRB, ICTR, and the JHCRN will provide you with tips and tools to: * Improve efficiency in regulatory […]

New Anti-Cancer Strategy


Fast facts: Changes to cells’ “skeletons” occur in conditions as diverse as cancer, chronic obstructive pulmonary disease and degenerative nerve diseases. Johns Hopkins researchers devised a way to screen potential drugs to see whether they affect cell skeletons. They identified a promising molecule that makes roaming cancer cells firmer so that they can’t easily colonize new areas. New Cancer-Fighting Strategy Would Harden Cells To Prevent Metastasis –Potential drug for pancreatic cancer now being tested in animals                     View video here. Video caption: Cell division (Credit: Janet Effler)   Existing cancer therapies […]

Tutorial: Scheduling a CRU Patient Using Epic 2012


If you are a research team member who schedules patients in the Clinical Research Units using the new Epic system, the ICTR’s Matthew Courtemanche has recorded a brief demonstration video that walks you through the scheduling process, step by step. To view the video click below: https://ictrweb.johnshopkins.edu/ictr/epic_demo/