ICTR in the News: Noninvasive Ultrasound Pulses Used to Precisely Tweak Rat Brain Activity

The following article profiles work performed by ICTR researcher Jordan Green, Ph.D., associate professor of biomedical engineering, who is also a member of the Kimmel Cancer Center and the Institute for Nanobiotechnology. Ultrasound pulses activate release of drugs from nanoparticles Biomedical engineers at Johns Hopkins report they have worked out a noninvasive way to release and deliver concentrated amounts of a drug to the brain of rats in a temporary, localized manner using ultrasound. The method first “cages” a drug inside tiny, biodegradable “nanoparticles,” then activates its release through precisely targeted sound waves, such as those used to painlessly and noninvasively … Continue reading

ICTR in the News: Allegheny Health Network Joins Johns Hopkins Clinical Research Network

The clinical research network is a program of the Johns Hopkins Institute for Clinical and Translational Research (ICTR), itself part of a national consortium aimed at transforming how clinical and translational research is conducted at academic health centers around the country. This article contains commentary from Daniel E. Ford, M.D., M.P.H., vice dean for clinical investigation at the Johns Hopkins University School of Medicine and director of the Johns Hopkins Institute for Clinical and Translational Research. Allegheny Health Network in Pennsylvania is the latest health system to join the Johns Hopkins Clinical Research Network. Developed by the Johns Hopkins Institute … Continue reading

ICTR in the News: Namandje Bumpus Named Science Commissioner

The following short article announces the appointment of ICTR researcher Namandje Bumpus, assistant professor of pharmacology and molecular sciences at the Johns Hopkins University School of Medicine. Namandje Bumpus, associate professor in the Division of Clinical Pharmacology, was nominated by the the mayor of the District of Columbia and confirmed by the city council as a science commissioner and the newest member of the Science Advisory Board in the District of Columbia. The board provides scientific oversight for the district’s Department of Forensic Science (DFS) and advises the DFS director, mayor and D.C. city council on matters relating to the department. Source: https://medicine-matters.blogs.hopkinsmedicine.org/2017/01/bumpus-named-science-commissioner/

Bloomberg School of Public Health creates scholarship opportunity for displaced Syrians

Two students will receive full tuition to school’s Masters of Public Health program Article By: Katie Pearce One of the many troubling spillover effects of the Syrian civil war is the disruption of the country’s health care field, including lost jobs and training opportunities for health workers. “There are thousands and thousands of Syrian health care workers who are either not able to practice or not able to continue their education because of the war,” says Paul Spiegel, who directs the Johns Hopkins’ Center for Humanitarian Health. To address this issue, Johns Hopkins is now offering a new opportunity for two … Continue reading

ICTR in the News: Personalized Treatment for Those in Blood Pressure ‘Gray Zone’

The following article profiles work performed by ICTR researcher J. William McEvoy, M.B.B.Ch., M.H.S., assistant professor of medicine and member of the Ciccarone Center for the Prevention of Heart Disease at the Johns Hopkins University School of Medicine. Coronary artery calcium score gives risk assessment to prevent over- or undertreatment of blood pressure Using data from a national study, Johns Hopkins researchers determined that using heart CT scans can help personalize treatment in patients whose blood pressure falls in the gray zone of just above normal or mild high blood pressure. Previously, the appropriate blood pressure treatment for these patients used … Continue reading

Apply to the Francis S. Collins Scholars Program

The Francis S. Collins Scholars Program in Neurofibromatosis Clinical and Translational Research provides formal training in the discipline of clinical translational science, the protected time to develop the skills appropriate for their research, exposure to translational research programs in government, academic, and industry environments and training in the care of patients with NF1. The program will provide up to 100% salary support for Collins Scholars, support for research costs, tuition for relevant coursework, travel costs for scientific meetings, mentor stipends, a curriculum for translational science expertise and a research community for clinical translational NF1 research. Scholars will be selected based on … Continue reading

ICTR in the News: U.S. patients often face costly ‘surprise’ medical bills from out-of-network specialists

Anesthesiologists, for example, charge almost six times what Medicare pays for the same service Article by: Stephanie Desmon The average anesthesiologist, emergency physician, pathologist, and radiologist charge more than four times what Medicare pays for similar services, often leaving privately insured consumers stuck with surprise medical bills that are much higher than they anticipated, new research published in the Journal of the American Medical Association suggests. The problem is that most patients do not actually choose these doctors with the highest markups, which mean they have no opportunity to anticipate how high their bills will be, say the researchers from the Johns … Continue reading

ICTR in the News: Potentially Reversible Changes in Gene Control ‘Prime’ Pancreatic Cancer Cells to Spread

The following article profiles work performed by ICTR researcher  Bert Vogelstein, M.D., professor of oncology at the Johns Hopkins University School of Medicine and the co-director of the Ludwig Center at the Johns Hopkins Kimmel Cancer Center. Epigenetic changes, not DNA mutations, drive some metastasis A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells. Those advantages, … Continue reading

ICTR in the News: Hospital Drones to Your House? (Video)

Featured in the below video is ICTR researcher Bruce Allen Leff, M.D., Director, The Center for Transformative Geriatric Research and a professor of medicine at the Johns Hopkins University School of Medicine. Source: http://www.politico.com/agenda/story/2017/01/video-hospital-drones-to-your-house-000273

Some Cells Need a ‘Haircut’ Before Duplicating

Study shows how and why hairlike structures on cells are lost Many of our cells are equipped with a hairlike “antenna” that relays information about the external environment to the cell, and scientists have already discovered that the appearance and disappearance of these so-called primary cilia are synchronized with the process of cellular duplication, called mitosis. Now, cell biologists at Johns Hopkins report the discovery of new information about how this “hair loss” and cell duplication are linked through the dramatic clipping of the tips of the cilia — what the scientists dub decapitation — that begins their disassembly. The … Continue reading

Longtime Congresswoman Barbara Mikulski Joins Johns Hopkins Faculty

Five-term U.S. senator from Maryland who spent four decades in Congress named professor of public policy, presidential adviser Article by: Dennis O’Shea Barbara A. Mikulski, the longest-serving woman in the history of Congress and Maryland’s longest-tenured U.S. senator, will join the Johns Hopkins University next week as a professor of public policy and adviser to the university’s president. Mikulski, who retired from the Senate earlier this month after completing her fifth six-year term, will participate in lectures, seminars, and symposia across the university. She will organize gatherings featuring nationally known policymakers and other leaders. “BEING AT JOHNS HOPKINS ENABLES ME TO … Continue reading