COVID-19 Research Opportunities for Employees

Health care workers and other essential employees play a key role in the COVID-19 pandemic.

Health care workers and other essential employees have an increased exposure to individuals with COVID-19 leading to a greater risk for developing the disease and an increase in the stress of the job. In an effort to learn more about the experiences of employees, multiple Johns Hopkins and national research protocols are inviting health care workers and other employees to participate in research and public health surveillance activities. As an employee, you should know that in every case it is a voluntary decision to join a research study or public health surveillance activity. If you do not participate in these activities, it will have no impact on your employment.

To help you make an informed decision about participating, we have created this website as a resource to learn about Johns Hopkins research studies and public health surveillance activities related to COVID-19 that seek to include employees. You may be able to join more than one of these studies but this is not always true. This limitation should be part of your decision to participate. All of the protocols listed are approved by the Johns Hopkins Medicine IRB.

A chart providing an overview of options is listed below. To learn more about any of the options listed, select ‘View Full Study Description’ to access a summary or contact the team using the contact number provided below.
 

Study & PITargetProcedures
LengthCompensationShares Test Results with Occup. HealthFull Study Description and Contact Information
Health Care Worker Exposure Response and Outcomes of Hydroxychloroquine Trial (HERO-HCQ Trial)

IRB00249289

PI: Mark Sulkowski
Health care workers 18 years or older who are at risk for COVID-19 infection.Blood draw, nasal swab for COVID-19 test, surveys and participants will take either a study drug or a placebo for 30 days.2 months and 2 visits$25 gift cardNoContact Kathleen Ward at kward27@jhmi.edu.

View Full Study Description
Johns Hopkins Medicine Hospital Worker COVID-19 Seroprevalence Study

IRB00249350

PI: Aaron Milstone
Johns Hopkins Medicine staff. Limited to 4,000 hospital workers.
Participation will be on a first come first served basis.
3 blood draws and questionnaires (at enrollment, 4 months later, and 8 months later)1 yearNoneNoTo determine eligibility click here.

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Moral Distress in the Midst of a Pandemic: A Survey

IRB00248237

PI: Adrian S. Dobs

Attending Physicians, Nurses, Respiratory Therapists, Residents, Fellows, Physician Assistants/ Nurse Practitioners, Physical Therapists/ Occupational therapists, Pharmacists, Social Workers, and Chaplains who are: • JHH Employees • JHU School of Medicine Employees • JHHS Employees • Employees at Sibley Memorial & Suburban Hospitals

Employees at the following JHCRN Sites:
• Anne Arundel Medical Center (AAMC) • Allegheny Health Network Cancer Institute (AHN) • Peninsula Regional Medical Center (PRMC) • Employees of Reading Hospital Tower Health (RH)

Members of Healthcare Professional Associations & Organizations Indicating Interest in Participating in this Survey (e.g., Maryland Nursing Association)
SurveysSurvey at 3 months and 6 monthsNoneNoContact Adrian Dobs at adobs@jhu.edu or Cynda Rushton at crushto1@jhu.edu.

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COVID-19 Observational Study of Health Care Workers (HCWs)

IRB0024895

PI: David Hager
Health care workers age 18 or greater, including nurses, advanced practice providers, respiratory therapists, paramedics, support staff, medical doctors who work clinically on the day of enrollment or would have worked clinically if scheduled to do so, and routinely worked clinically since 2/1/2020 in an environment at high risk for exposure to patients with COVID-19.Surveys and blood draws (which will be assessed at the Centers for Disease Control & Prevention for evidence of COVID-19 seroconversion)Approximately 60 days and 2 visitsNoneNoContact David Hager at dhager1@jhmi.edu or 410-614-6292

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Investigation of SARS-CoV-2 Seroprevalence among Targeted Populations--Department of Health (DC Health) in Partnership with the Department of Forensic Sciences (DFS) Seroprevalence Survey

IRB00252021

PI: Mark Sulkowski
People working at Sibley Memorial Hospital in Washington DC.Questionnaire and blood draws to conduct serology testing4-6 weeksNoneNoTo determine eligibility click here.

For questions, contact the DC Health COVID-19 call center at 202-576-1117.

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Serosurvey of Emergency Department Frontline Healthcare Professionals (HCPs) at the Johns Hopkins
Hospital during COVID-19

IRB00248722

PI: Richard Rothman
Healthcare Professionals who work primarily in the Adult and Pediatric Emergency Departments at the
Johns Hopkins Hospital (including but not limited to: full time attending physicians, residents, nurses, CNAs,
ED technicians, security staff, environmental service staff, social workers, and respiratory therapists [who
are assigned to staff the ED]). Must be ≥18 years of age.
Questionnaire, 3 blood draws and 3 finger sticks to test for the presence of antibodies against SARS-CoV-28 months, 3 visits and weekly questionnaires$10 for each weekly questionnaire completedNoTo determine eligibility, click here.

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Convalescent Plasma to Stem Coronavirus: A Randomized, Blinded Phase 2 Study Comparing the Efficacy and Safety Human Coronavirus Immune Plasma (HCIP) vs. Control (SARS-CoV-2 Non-Immune Plasma) among Adults Exposed to COVID-19

IRB00245634

PI: Shmuel Shoham
Adults 18 years or greater who are without COVID-19 symptoms, but have had close contact with or significant exposure to a person with COVID illness. This includes healthcare workers (clinical staff, environmental services, dining services, etc.) and/or household contacts of a COVID patient, at risk of developing COVID illness. One plasma infusion through an IV; blood tests, nasal swabs, physical exam, and questionnaires; and telephone follow up calls Up to 7 in-person visits over 3 monthsUp to $200 (total compensation)NoContact Jeanette Marchesi at 443-326-7725 or visit http://covidplasmatrial.org.


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COVID-19 and Telehealth in the Intensive Care Unit Setting

IRB00251885

PI: Sarah Nelson
Medical directors and/or nursing leadership of ICUs in the JHM system (JHH, JHB, Howard County General, Suburban and Sibley)A brief survey (2-5 minutes)2-5 minute survey, no visits requiredNonen/aContact Sarah Nelson at snelso43@jhmi.edu or 443-287-2989.

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A Proactive Risk Assessment to Identify Barriers to and Strategies for Appropriate Social Distancing among Health Care Workers during the COVID-19 Pandemic

IRB00251728

PI: Sara Keller
18 years or older health care workers working in Nelson 3 at JHHQuestionnaire20-20 minute phone interview$10 gift cardn/aContact Alejandra Salinas at asalina4@jhmi.edu.

All unit staff in Nelson 3 will also be notified directly of the study by their unit director and the study team.

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Optimal Reuse of N95 Respirator during Pandemics with Aerosol-Transmitted Pathogens

IRB 00252433

PI: Valeria Fabre
JHH physicians and nurses who care/cared for COVID-19 patients while wearing an N95An electronic anonymous survey regarding experience and perceptions around N95 reuse.
Fit-testing of reused N95s.
3 minute questionnaire and Fit tests will be done at least
once and up to the point of failure or structural damage.
$10 gift card and a new N95 (if you fail a fit-test)n/aContact George Jones at gjones65@jhmi.edu.

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Convalescent Plasma to Limit Coronavirus Associated Complications: A Randomized, Double-Blind, Controlled,
Phase 2 Study Comparing the Efficacy and Safety of Human Coronavirus Immune Plasma (HCIP) vs. Control (SARS-CoV-2
non-immune) Plasma Among Outpatients with Symptomatic COVID-19

IRB00247590

PI: David Sullivan
Adults 18 years or greater with symptoms consistent with COVID-19 illness and a positive SARS-CoV-2 PCR within 8
days of enrollment.
Questionnaire, one plasma infusion, either control or convalescent antibodies, through an IV, blood tests, nasal swabs, physical exam, telephone follow up calls
daily vital signs and symptoms log, maintained by the participant.
Up to 5 visits to a nearby study center over 90 daysUp to $200NoContact Sonali Thapa at sthapa8@jhu.edu.

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Improving HCW Safety through Appropriate PPE Use During the COVID-19 Pandemic: A Human Factors
Engineering (HFE) and Implementation Approach

IRB00248695

PI: Ayse Gurses


Health care workers working in the emergency department and home health care during the
COVID-19 pandemic.
Interviews and focus groups to describe experiences using PPE.Varies between 30 minutes and 1 hour NoneNoContact the study team at 410-900-4255.

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A Proactive Risk Assessment to Identify Barriers to and Strategies for Appropriate Social Distancing among Health Care Workers during the COVID-19 Pandemic

IRB00251582

PI: Sara C. Keller
18 years or older health care workers working in Nelson 3 at JHHBluetooth monitoring and observations of physical distancing practices on unit floor.Bluetooth monitoring over a 4 month period and 2 observations over a 2 month period.Nonen/aNelson 3 unit director and study team will disseminate bluetooth monitors on the unit floor.

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Support for Health Care Workers and Direct Services Staff

PI: Tener Veenema
All KKI, JHMI and JHU employees over 18 years who work in a health care setting and their family members over 18 years (if interested)Survey and interviews15 minute survey and interview that lasts 20 minutes up to 2 hours$10 gift card for survey completion and $50 gift card for interviewsn/aContact Tener Veenema at tveenem1@jhu.edu.

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