Category Archive: Child of CRUs

Research Coordinator Support Service


The ICTR Research Coordinator Support Service (RCSS) is a pool of research coordinators that are available for hire on a part-time basis by Johns Hopkins researchers. These coordinators are able to handle a wide range of responsibilities, and the support can be customized to best fit the needs to each individuals’ research team.  The pool consists of study coordinator apprentices who are a part of the Study Coordinator Apprenticeship and Mentoring Program (SCAMP) and Research Coordinators. These coordinators are available as part of a fee for service program, which makes the process of finding a part-time coordinator easier, as well … Continue reading

Future Charges For Clinical Research Unit Services


Effective May 2018 The National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health (NIH), which supports the ICTR Clinical Research Units (CRUs) through its Clinical and Translational Science Award (CTSA) program, announced in 2014 that direct support of the CRUs will not be allowed for any new or re-competing CTSA awards.  Our CRUS have been a major source of support for investigators throughout Johns Hopkins and this change in policy will have a significant impact on our future ICTR operations.  This NCATS policy has already been implemented for the 18 CTSA “hubs” that received a new award … Continue reading

Pediatric Neuropsychological Testing


Neuropsychological testing, includes achievement tests, behavior checklists, measures of personality, developmental status, intelligence, executive function, language, visual spatial skills, and memory, are available to ICTR CRU investigators. Skilled psychologists are available to provide a broad range of testing, including assessments of children who are cognitively very limited; those less severely impaired; and learning disabled children and adults; and control groups.

Neuroimaging


Neuroimaging resources available through the NBRU include structural and functional magnetic resonance imaging, spectroscopic and diffusion analysis, fiber track mapping, fMRI protocol development, and training of pediatric and brain/behavior disordered subjects to cooperate with research protocols including motion control during scans. The F.M. Kirby Research Center for Functional Brain Imaging is dedicated to brain research using functional MRI technologies and is specifically designed to provide a uniquely comfortable scanning environment for studies in children, the elderly, and subjects with neurological and psychiatric disorders.

Operant Performance Measures


State-of-the-art Operant Performance Measures are available to investigators through the NBRU at Kennedy Krieger Institute. Direct observation of behavior, conducted in areas that simulate naturalistic settings, is accomplished by the use of computers with accompanying customized software that allows for the simultaneous recording of up to twenty behaviors for real time analysis, including conditional probability calculations.

Pediatric Motion Analysis Laboratory


The Pediatric Motion Analysis Laboratory is available through the NBRU in the Kennedy Krieger Institute. The lab provides whole-body movement assessments that quantify discrete components of the mechanisms of movement and movement deficits and detect very small changes in performance over time or in response to treatment. Several techniques are used to quantify movement, including: three-dimensional tracking and reconstruction of movement kinematics, force plate recordings, recordings of muscle activity, and calculation of joint forces and torques.

Research Participant Advocacy


Research Participant Advocacy (RPA) Program The RPA serves as a resource to volunteers. Contact us for an independent witness to the consent process, to serve on the volunteers behalf in the case of a misunderstanding between the volunteer and study team, or to provide information about research in general or a specific protocol. The Research Participant Advocacy Office provides consulting expertise on human subjects and regulatory issues, including IRB applications, the informed consent process, study feasibility and good clinical practice (GCP). Contact us for quick expert help. The RPA reviews applications to the Clinical Research Unit to assure high standards … Continue reading

Nursing Research Resources


A broad scope of nursing services is offered in the CRUs, ranging from routine vital signs to intensive studies requiring intravenous infusions and specialized measures. Some examples of nursing services include assisting with intravenous glucose tolerance tests and insulin clamps, intravenous infusion of approved and investigational drugs, specialized strength and joint testing, calculation of body mass index and body fat content, gynecologic examination, and polysomnography for sleep studies. Our nursing staff also participate in off-site research for subjects living in Baltimore.  

Exercise Physiology and Body Composition


The Exercise Physiology and Body Composition Core’s laboratory provides DEXA measurements for body fat, muscle and bone composition, metabolic stress testing, and also supports exercise-training protocols. The facilities are located at the Bayview Clinical Research Unit and at the Green Spring Station Outpatient Clinic. DEXA scanning is also available on the Broadway campus through the Adult Outpatient Unit. Supported studies address issues like exercise testing and training and body composition of patients with chronic health conditions. The Core also provides coronary risk factor assessment and modification for approved users and works closely with CRU Research Nursing, Research Nutrition, and the … Continue reading

Research Nutrition


ICTR Research Nutrition was established to support CRU investigators in developing and implementing the best nutritional plans for their research protocols for both pediatrics and adults. Services are located in the clinical research units at both the Johns Hopkins Bayview Campus and the Broadway (main medical) Campus. Research Nutrition staff includes a diverse nutrition team comprised of a research nutrition manager, research nutritionists, a kitchen supervisor, and research nutrition technicians. The ICTR Research Nutrition staff can perform: In-depth nutrition assessments Diet intake analysis for both macro- and micro-nutrients Nutrition counseling Anthropometric and body composition measurements, Energy expenditure assessments Design and … Continue reading

Cardiovascular Imaging Laboratory


The Cardiovascular Imaging Laboratory is located at the Bayview CRU and is supervised by Pamela Ouyang, MBBS, ICTR Deputy Director and Director of the Johns Hopkins Women’’s Cardiovascular Health Center. The Core provides echocardiographic and carotid imaging for approved CRU protocols, as well as measurement of endothelial function and arterial stiffness. The Cardiovascular Imaging Laboratory provides the following services and equipment: Echocardiogram Echocardiograms are performed on a Toshiba Artida ultrasound system. All cardiac studies are stored digitally and analyzed using the Philips Excelera System. Image acquisition and analysis protocols can be customized to meet the unique needs of the investigator. … Continue reading