Timeline

 

YearEntityEvent
1997Congress1st U.S. law to require trial registration (FDAMA)
2000NIHReleases ClinicalTrials.gov website
2005ICMJERequires registration before enrollment
2006WHOAll clinical trials should be registered
2007CMSPI must enroll qualifying clinical trials in ClinicalTrials.gov
2007CongressExpanded registration, submission of results and adverse events, civil penalties (FDAAA)
2008NIHReleases results database
2015CMSMandatory Reporting of Clinical Trial Number on Claims