Pamela Ouyang, MBBS

ICTR Deputy Director for the Bayview Medical Center

Associate Program Director for the ICTR Clinical Research Units

Professor of Medicine, The Johns Hopkins University School of Medicine

After completing medical school and initial postdoctoral training in the UK, Dr. Ouyang’s career at Johns Hopkins began with residency and fellowship training in cardiology. Following the completion of her fellowship in 1980, she joined the faculty of the Johns Hopkins University School of Medicine, where she is now a full professor in the Department of Medicine’s Division of Cardiology. In addition to her clinical and research contributions, Dr. Ouyang teaches students, residents and fellows from both Johns Hopkins Hospital and the Johns Hopkins Bayview Medical Center.

Dr. Ouyang was appointed associate director of the Johns Hopkins Bayview Medical Center General Clinical Research Center (now part of the ICTR Clinical Research Units) in 1997, and became its program director in 2001. She is an attending cardiologist at the Bayview, caring for patients in the Coronary Intensive Care Unit, and served as the director of Cardiology Outpatient Services there from 1989 to 1997. Dr. Ouyang is currently developing the Johns Hopkins Women’s Cardiovascular Health Center to better serve her patients on the Bayview campus.

Education and Training

  • BS (Physiology, 1st Class Honors), University of London, London, United Kingdom, 1971
  • MBBS (Honors in Medicine), St. Bartholomew’s Hospital Medical School, London, United Kingdom, 1974
  • House Surgeon, Royal Berkshire Hospital, Reading, Berkshire, United Kingdom, 1975
  • House Physician, St. Bartholomew’s Hospital, London, United Kingdom, 1975
  • Senior House Officer, London Chest Hospital, London, United Kingdom, 1976
  • Junior Assistant Resident, Pennsylvania Hospital, Philadelphia, Pennsylvania, 1976
  • Fellow, Cardiovascular Division, Johns Hopkins Hospital, Baltimore, MD, 1976-1978
  • Assistant Resident, Johns Hopkins Hospital, Baltimore, MD, 1978-1980

Accomplishments, Recognition, and Service

In 2005, Dr. Ouyang became a Fellow of the American Heart Association and the Council on Epidemiology and Prevention. In 1999, Dr. Ouyang was chosen as one of the top ten faculty members in the Department of Medicine at Bayview and is consistently identified by the internal medicine hospital staff as an excellent role model. In 2002, she was selected to participate in the Johns Hopkins Medicine 2002 Leadership Development Program.

Dr. Ouyang has published more than 100 peer-reviewed articles, invited articles and book chapters, and has delivered 80 invited lectures since 1982. She serves as an editor for five peer-reviewed journals, including Annals of Internal Medicine, Journal of American College of Cardiology, American Journal of Physiology, Heart and Circulatory Physiology, Archives of Internal Medicine, and American Journal of Cardiology.

Some of Dr. Ouyang’s administrative appointments include nearly a decade of service to the Bayview Medical Center’s Institutional Review Board (1989-1997), two years on the Advisory Committee for the Department of Medicine Task Force on Women’s Academic Careers in Medicine (2008-2010), and current service as a member of the Faculty Advisory Group, A Woman’s Journey, and as a member of the Advisory Committee for the Department of Medicine Task Force on Women’s Academic Careers in Medicine.

Clinical and Research Interests

  • Clinical: ischemic heart disease, cardiovascular disease in women
  • Research: vascular effects of sex hormones, subclinical atherosclerosis, clinical trials in cardiology

Dr. Ouyang’s areas of research include studies in ischemic heart disease. In recent years, her work has focused on cardiovascular disease in women including research on the effects of hormone replacement therapy in women with coronary artery disease and coronary bypass grafts. She has a particular interest in sex differences in atherosclerotic cardiovascular disease. This research includes the evaluation of the effects of risk factors, including sex hormones, on vascular responses, the interaction between sex hormones and metabolic syndrome, and ways to improve the assessment of coronary disease in women.

Two current grants for which Dr. Ouyang serves as principal investigator and co-investigator, respectively, are funding a dose ranging study of the effects of alpha lipoic acid on oxidative stress, and a Multi-Ethnic Study of Atherosclerosis (MESA).